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NEW QUESTION: 1
In a Fishbone Diagram the 6M's stand for Methods, Measurements, Machine, Man, Mother Nature and
____________ .
A. Management
B. Medical
C. Merger
D. Materials
Answer: D
NEW QUESTION: 2
Which of the following is true regarding extent of absorption of drugs?
A. Drugs which are too lipophilic cannot cross the lipid cell membrane
B. After oral ingestion of drugs, the absorption of drug may be incomplete
C. Drugs which are too hydrophilic are not soluble enough to cross the water layer adjacent to the cell
D. Grape juice activates P-glycoprotein leading to substantial inhibition of absorption of drugs
E. P-glycoprotein is an efflux transporter which is present in the enterocytes and it enhances the absorption of drug
Answer: B
Explanation:
Explanation
It is not necessary that all the drugs get completely absorbed after oral administration. Most of them are incompletely absorbed. The extent of absorption varies from 5 to less than 100 % with oral ingestion of drugs.
Drugs which are too hydrophilic like atenolol are incompletely absorbed because the drug cannot cross the lipid membrane due to high hydrophilic nature of the drug. Similarly, drugs which are too lipophilic like acyclovir are not soluble enough to cross the water layer adjacent to the cell. P-glycoprotein is an efflux transporter which is present in the enterocytes and it inhibits absorption of drug. It is also known as export transporter or reverse transporter. It has many drugs as its substrate. Grape juice in fact inhibits P-glycoprotein in the intestine thereby decreasing the efflux of drug from the cells by P-glycoprotein. Thus ingestion of grape juice may lead to significantly increased absorption of the drug.
NEW QUESTION: 3
The operations department of a major hosting provider is under pressure to deliver services more quickly. They have a significant number of tools for managing IT technologies across the data center.
Although investments in virtualization and automation have been made, it still takes months to provision basic IT services to meet new customer demands. The provider is considering offering cloud services.
What is a key focus area for driving higher operational efficiency and associated profits?
A. Strengthen the architecture to ensure that the components within the data center are modular and can be reused.
B. Deliver custom services using automation tools. Apply change control to the tools to minimize change. Develop reusable components to build environments.
C. Deliver customer services that are derived from an approved set of service templates. Apply change control to manage the life cycle of the templates.
D. Deliver a custom capability for each customer based on analysis of the application architecture. Use shared services where possible.
Answer: C
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